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Quake

Quake is an FPS from iD Software. You play as a grunt who must travel to a variety of worlds through interdimensional portals and destroy a Lovecraftian horror and hundreds of minions before they can locate and overrun earth. Dark Places is a source port that has various enhancements over the official versions.
It may not be as impressive graphically as say, Tenebrae, but this port is the widescreen king of source ports, so it gets the honors here. Dark Places can be downloaded here (original Quake data is required and not included) http://www.icculus.org/twilight/darkplaces/

Enemy Territory: Quake Wars

Enemy Territory - QUAKE Wars is a team based FPS from ID Software.Game play is similar to Battlefield 2142.This game also has G15 Keyboard support.

Tomb Raider: Anniversary

Created with an advanced version of the engine used for Lara Croft Tomb Raider: Legend, the gameplay mechanics, artificial intelligence and level puzzles of Tomb Raider: Anniversary are now more refined, in-depth and complex. Now fans can explore the original adventure on a much grander scale, while enjoying the elements which made the original such a success.

Jade Empire

You play as an martial arts student who is trying to rescue his/her abducted Master from a group of assassins. While unveiling the circle of treachery, you can choose to follow the Way of the "Open Palm" or the "Closed Fist" (Good/Evil - much like the KotOR series) and influence the story and people in this way.

Sacrifice

Take control of alien wizards as they seek to control manaliths and banish their opponents from the realms. Harvest the souls of your enemies' creatures and create more powerful, deadly beings to ravage the lands. Sacrifice your own followers to destroy your opponent's altar and claim victory. Master the spells given to you by the five gods of this new world: the righteous god of Life, Persephone, the humble god of Earth, James, the all-knowing god of Air, Stratos, the industrious god of Fire, Pyro, and the sinister god of Death, Charnel.

You Are Empty

You Are Empty is a first-person action game, that offers players an alternative approach to the history of USSR. In the late fifties of the XX century, leading Soviet scientists start experiments that alter human physiology and mentality in order to create super humans capable of building a bright future for communism all over the world. But tampering with the universes' toolbox is not without consequence. As a result, the experiments break free of their creators and go on a rampage throughout the city.

CellFactor: Revolution

After a series of cataclysmic events, the planet is now dominated by a massive corporate superpower known as the LIMBO corporation. Limbo's sole purpose is to advance technology in bold new ways, regardless of the human cost. This pursuit of technology led LIMBO to maintain control over what remains of the human race through the development of an advanced army of super-powered soldiers, some of which possess a new kind of telekinetic ability that LIMBO calls PSI powers.In the game you battle on both sides of the war, the LIMBO corporation and the human resistance known as GUARD.

Mafia: The City of Lost Heaven

Mafia is a third person action-adventure game in the vein of GTA. The game takes place in a fictional 1930's city.

Hitman: Blood Money

Hitman: Blood Money is the fourth game of the Hitman series from Io-Interactive and Eidos. Once again Agent 47 uses either stealth or sheer firepower to assasinate his Agency's contracts.

Tortuga - Two Treasures

Tortuga - Two Treasures is a pirate-themed action game from Ascaron Entertainment and CDV Software, and a plotwise sequel to the strategy game "Pirates of the New world." You play as Thomas "Hawk" Blythe, an 18th century buccaneer who looks and acts like a combination of Captain Jack Sparrow and Han Solo. You must search the Spanish Main for the lost treasure of Sir Henry Morgan.