In Windows 8, I had quite a bit of trouble with this, changing the registry keys at HKLM...\Homeworld didn't do ANYTHING and it was very frustrating. Finally, it occurred to me to do a search, and it turns out the proper settings were hidden in HKEY_CURRENT_USER\Software\Classes\VirtualStore\MACHINE\SOFTWARE\Wow6432Node\Sierra On-Line\Homeworld
Of course, for me, changing them did not result in a playable 16x9 game.. it did cause the game to render in 1920x1080.. but the main menu was drawn all the way across the screen with the actual clickable area not stretched, and crazy "trails" effects on the mouse pointer, while in actual gameplay it drew everything in a 4x3 square on the left edge of that rectangle, with fonts crushed into unreadable blobs. I don't know if this has anything to do with the fact that windows 8 insists on giving a popup as the game launches asking me what to do with the game CD. Guess I've got to settle for playing it in a 4x3 window (or change monitor settings every time I launch it to force a windowbox)
Edit: (I forgot to mention, but it's worth noting; my failure here is likely related to the fact that I am unable to follow the instructions with this game running in Win 8, because it refuses/fails to set any mode that uses OpenGL. I've had trouble finding out what might be up with that; I've seen a lot of threads from people talking about Win 8 not having OpenGL support, but that seemed to be an issue of early drivers not having the functionality, I have obtained the latest drivers which should be fine, and I'm almost positive that other games successfully render using OpenGL.)
