As it stands right now, the answer is no, because the highest supported with TH2go is 5040x1050, and that was patched in only recently.
In the future? I'm not sure. Right now, there's some sort of limit in Vista as to how big of a display you can have, which is what the current display size is just barely under, so that's one thing that needs to be out of the way first.
Outside of that, I'm sure some more informed individuals could tell you why/why not this can/cannot happen... It would take one hell of a video card combination to drive the thing though, that's for sure... :D
not really with SLI cards and future cards will only get faster.
if you play older games you can probably run 3x1920x1200 without too much problem. and with never games you may set the setting to medium instead of high