I have no experimental experience to give a concrete solution. Sorry
Anecdotally and from experience (Previously owned 3 x 24" Dell U2414H 1080p on a single 980Ti, upgraded to 3 x Acer CB241HQK 23.6" 4k, on a single 1080Ti), I think it's possible within the hardware you mentioned without the MST hub (honestly, never heard of this device). Display Port and DP 1.2 allows for 4 displays daisy chained @ 1080p, capped at 60 Hz I think? (
http://multimonitorcomputer.com/solved/ ... -guide.php). I used to daisy chain 2 displays at 1080p with no problem on the 980Ti.. Good luck. Look forward to hearing about your results.