In the Profile Manager, where you save you profile, there's a tab labeled "Activation". On that tab, you can have CCC generate a shortcut and/or hotkey assignment to load that profile in the future. Just select whichever you desire (or both) and when you save that profile s shortcut will go to your desktop and the hotkey will be active. The hotkey modifiers can be any 2 or 3 key combination of ALT, CTRL, SHIFT - along with a key.
I use shortcuts and shoved them into a custom Toolbar, as I prefer a blank desktop:
God damn, Snipping Tool sure is handy.